Population: Patients receiving pars plana vitrectomy alone and PPV combine with scleral buckle for rhegmatogenous retinal detachment

Setting: Postoperative clinic-based environment

Intervention: Pars plana vitrectomy and scleral buckle

Comparison: Pars plana vitrectomy

Outcomes

Relative effect: RR (95% CI)

Number of studies

Certainty of the evidence (GRADE)^†

Rationale

Final BCVA

WMD = −0.17, 95% CI = [0.27, 0.07], p = 0.001

2

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Low

1. Low sample size

2. Few diversities of studies

3. No heterogeneity

4. Low-to-moderate study risk of bias

5. The included studies are Prospective and retrospective.

6. Significant difference

Missing statistical analysis

Macular edema

RR = 0.36, 95% CI = [0.74, 0.18], p = 0.006

4

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Low

1. Low sample size

2. Few diversities of studies

3. No heterogeneity

4. Low-to-moderate study risk of bias

5. The included studies are Prospective and retrospective.

6. Significant difference

Missing statistical analysis

Proliferative vitreoretinopathy

RR = 1.18, 95% CI = [1.90, 0.74], p = 0.48

4

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Medium

1. High sample size

2. Moderate diversity of studies

3. Low heterogeneity

4. Low-to-moderate study risk of bias

5. All included studies are retrospective.

6. Non-significant difference

No inconsistency, indirectness, imprecision, major study limitations or publication bias