Anatomical Disorder

Pathological mechanism reducing visual acuity


Impairment of the photoreceptors in the fovea

Disruption of the inner and/or outer segments of photoreceptors

Probably irreversible*

Impairment of the neurons in the inner retina

Neuronal loss in either the inner nuclear layer (INL) or the ganglion cell layer (GCL) due to ischemia in the inner retina


Neuro-retinal swelling due to macular edema

Light scattering resulting in a reduced amount of light received by photoreceptors at the fovea Compromised neural transduction from photoreceptors to inner retinal neurons