Mean ± SD (mmHg)

Travoprost 0.004% group n = 31

Travoprost 0.004%/timolol 0.5% group n = 31

P-value

IOP (first visit)

26.4 ± 2.1

26.3 ± 2.1

P = 0.955

IOP (after 3 months)

18.6 ± 1.6

17.8 ± 1.4

P = 0.132

Diff. IOP 3/1

−7.8 ± 2.3

−8.5 ± 1.9

P = 0.148

IOP (after 6 months)

19.1 ± 1.4

18.1 ± 1.2

P = 0.010

Diff. IOP 6/1

−7.3 ± 2.4

−8.2 ± 2.3

P = 0.004

IOP (after 12 months)

19.9 ± 1.4

18.2 ± 1.4

P = 0.000

Diff. IOP 12/1

−6.5 ± 2.4

−8.1 ± 2.0

P = 0.014

IOP (after 24 months)

20.3 ± 1.4

18.7 ± 1.7

P = 0.000

Diff. IOP 24/1

−6.1 ± 2.9

−7.6 ± 2.3

P = 0.032