Sample characteristics (n)


Main outcome

Abd El-Kader et al., 2013

Obese type 2 diabetic patients n = 50

Moderate and mild aerobic exercise training, three times/week for 3 months.

↓Leptin, TNF- α, IL2, IL4, IL6, HOMA-IR and HBA1c

Krause et al., 2014

Male adults sedentary with obesity and type 2 DM n = 25

Low or moderate intensity exercise for 30 min, three times per week.

↑Muscle nNOS and tNOx in controls

↑Plasma catalase increased in T2DM

No differences in plasma inflammatory markers

Ordonez et al., 2014

Premenopausal obese young women with Down syndrome n = 20

Aerobic training, three sessions per week for 10-week with a work intensity of 55% - 65% of peak heart rate.

↓TNF-α, IL-6 and high sensitive CRP in plasma

↓Percentage of fat

Ryan et al., 2014

Overweight and obese sedentary postmenopausal women n = 77

Aerobic exercise training 3 days a week for six months.

↓ ICAM-1 mRNA expression


↓Fat mass, visceral fat, triglycerides, insulin resistance, waist circumference and CRP

Trachta et al., 2014

Obese women with arterial hypertension n = 15

Aerobic exercise for 30 min, 3 times a week for three-month

No changes in TC, LDL-C, HDL-C and triglycerides, leptin, insulin and adiponectin concentrations

↑In insulin sensitivity, HOMA-IR


Sang et al., 2015

Patients with Metabolic Syndrome n = 39

Walk/run training program 5 times a week for 10 week

No changes TC, LDL-C, HDL-C and triglycerides


↑ Sub-fraction of HDL-c