Variables

(n = 74)

Pretreatment Responder

(n = 49)

pretreatment parameters of Non-responder (n = 25)

P value

Platelet count (Mean ± SD)

PLT (10³/µl)

168.57 ± 64.49

104.80 ± 61.65

<0.0001***

Liver function tests (Mean ± SD)

Bilirubin (mg/dl)

1.33 ± 0.37

1.96 ± 0.68

<0.0001***

Albumin (gm/dl)

3.77 ± 0.61

3.03 ± 0.49

<0.0001***

ALT (U/L)

65.35 ± 25.39

69.36 ± 44.33

0.622

AST (U/L)

62.22 ± 19.40

56.68 ± 29.00

0.331

INR

1.19 ± 0.22

1.54 ± 0.26

<0.0001***

Factor IV collagen (mg/dl)

179.37 ± 76.04

296.80 ± 122.06

<0.0001***

HBV DNA PCR level (IU/ml) (N.%)

Mild viral load

17 (34.69%)

8 (32%)

0.118

Moderate viral load

16 (32.65%)

9 (36%)

High viral load

16 (32.65%)

8 (32%)

Liver Fibroscan (kPa'') (Mean ± SD)

9.89 ± 2.92

16.10 ± 5.59

<0.0001***

FIB-4 score (Mean ± SD)

2.09 ± 1.10

4.19 ± 1.56

<0.0001***

APRI score (Mean ± SD)

1.09 ± 0.61

1.53 ± 0.70

0.007**