| Variables (n = 74) | Before therapy | After one year of entecavir therapy | P. value |
| Platelet count (Mean ± SD) PLT (103/µl) | 147.03 ± 70.04 | 182.97 ± 76.22 | 0.002** |
| Liver function tests (Mean ± SD) |
| ||
| Bilirubin (mg/dl) | 1.55 ± 0.58 | 1.31 ± 0.42 | 0.224 |
| Albumin (gm/dl) | 3.52 ± 0.67 | 3.62 ± 0.55 | 0.0001*** |
| ALT (U/L) | 66.70 ± 32.76 | 37.38 ± 20.46 | 0.0001*** |
| AST (U/L) | 60.35 ± 23.67 | 31.89 ± 14.87 | 0.0001*** |
| INR | 1.31 ± 0.29 | 1.23 ± 0.24 | 0.111 |
| HBV DNA PCR level (IU/ml) (N%) Mild viral load Moderate viral load High viral load |
25 (33.80%) 25 (33.80%) 24 (32.40%) |
Undetectable |
------ |
| Factor IV collagen (mg/dl) | 219.04 ± 108.76 | 171.34 ± 78.25 | 0.012* |
| Liver Fibroscan (Kilo Pascal'' kPa'') (Mean ± SD) | 11.99 ± 4.96 | 10.70 ± 5.80 | 0.001 ** |
| Fibrosis stage (N %) (Mean ± SD) F0 F1 F2 F3 F4 |
------- ------- 29 (39.19%) 8.12 ± 0.59 30 (40.54%) 11.49 ± 1.43 15 (20.27%) 20.46 ± 3.85 |
4 (5.41%) 5.17 ± 0.20 17 (22.97%) 6.11 ± 0.19 24 (32.43) 7.76 ± 0.80 15 (20.27%) 12.45 ± 1.03 14 (18.92%) 21 ± 4.01 |
---------- ---------- 0.018* 0.023* 0.972 |
| FIB-4 score (Mean ± SD) | 2.80 ± 1.61 | 1.56 ± 1.02 | 0.0001*** |
| APRI score (Mean ± SD) | 1.24 ± 0.67 | 0.50 ± 0.28 | 0.0001*** |