Single item PAC-QoL | Comparison versus Placebo | ||
Odds ratio | (95% confidence interval) | p-value | |
1: Have you felt bloated to the point of bursting? | 3.412 | (2.517, 4.624) | <0.0001 |
2: Have you felt heavy because of your constipation? | 5.931 | (4.312, 8.160) | <0.0001 |
3: Have you felt any physical discomfort? | 2.576 | (1.910, 3.474) | <0.0001 |
4: Have you felt the need to open your bowel but not been able to? | 5.157 | (3.776, 7.043) | <0.0001 |
5: Have you been embarrassed to be with other people? | 1.563 | (1.134, 2.156) | 0.0064 |
6: Have you been eating less and less because of not being able to have bowel movements? | 3.023 | (2.200, 4.155) | <0.0001 |
7: Have you had to be careful about what you eat? | 2.545 | (1.874 , 3.456) | <0.0001 |
8: Have you had a decreased appetite? | 1.875 | (1.361, 2.583) | 0.0001 |
9: Have you been worried about not being able to choose what you eat (for example, at friend’s)? | 2.365 | (1.689, 3.313) | <0.0001 |
10: Have you been embarrassed about staying in the toilet for so long when you were away from home? | 1.434 | (1.067, 1.928) | 0.0170 |
11: Have you been embarrassed about having to go to the toilet so often when you were away from home? | 0.837 | (0.622, 1.127) | 0.2407 |
12: Have you been worried about having to change your daily routine (for example, travelling, being away from home)? | 0.894 | (0.665, 1.203) | 0.4599 |
13: Have you felt irritable because of your condition? | 3.004 | (2.207, 4.088) | <.0001 |
14: Have you been upset by your condition? | 3.413 | (2.501, 4.656) | <0.0001 |
15: Have you felt obsessed by your condition? | 2.148 | (1.576, 2.927) | <0.0001 |
16: Have you felt stressed by your condition? | 2.405 | (1.775, 3.257) | <0.0001 |
17: Have you been less self−confident because of your condition? | 1.671 | (1.223, 2.282) | 0.0012 |
18: Have you felt in control of your situation? | 1.650 | (1.236, 2.203 | 0.0007 |
19: Have you been worried about not knowing when you are going to be able to open your bowels? | 1.783 | (1.328, 2.394) | 0.0001 |
20: Have you been worried about not being able to open your bowels when you needed to? | 3.615 | (2.663, 4.908) | <0.0001 |
21: Have you been more and more bothered by not being able to open your bowels? | 3.845 | (2.819, 5.244) | <0.0001 |
22: Have you been afraid that your condition will get worse? | 3.314 | (2.422, 4.535) | <0.0001 |
23: Have you felt that your body was not working properly? | 3.214 | (2.377, 4.344) | <0.0001 |
24: Have you had fewer bowel movements than you would like? | 7.566 | (5.468, 10.470) | <0.0001 |
25: Have you been satisfied with how often you open your bowels? | 7.336 | (5.319, 10.118) | <0.0001 |
26: Have you been satisfied with the regularity with which you open your bowels? | 6.160 | (4.508, 8.418) | <0.0001 |
27: Have you been satisfied with your bowel function? | 6.711 | (4.894 , 9.201) | <0.0001 |
28: Have you been satisfied with your treatment? | 4.162 | (4.508, 8.418) | <0.0001 |