Adjusted* mean (SE)

Comparison vs. Placebo

Placebo

SPS/BIS

Adjusted* mean (SE)

95% confidence interval

p-value

Worries and concerns

0.20 (0.04)

0.68 (0.03)

0.48 (0.05)

(0.37, 059 )

<0.0001

Physical discomfort

0.35 (0.05)

1.09 (0.04)

0.73 (0.07)

(0.61, 0.86 )

<0.0001

Psychosocial discomfort

0.19 (0.04)

0.41 (0.03)

0.22 (0.05)

(0.11, 0.32 )

<0.0001

Satisfaction

0.35 (0.07)

1.57 (0.05)

1.22 (0.08)

(1.05, 1.38 )

<0.0001

Overall score

0.28 (0.05)

0.94 (0.03)

0.65 (0.06)

(0.54, 0.77 )

<0.0001