Reader | Sensitivity | Specificity | PPV | NPV | Accuracy |
Lymphangioleiomyomatosis (N = 30) | |||||
Rad-specialists 1-2 | 90 (84 - 96) | 99 (96 - 99) | 97 (93 - 99) | 96 (92 - 99) | 96 (92 - 99) |
Rad-specialists 3-4 | 80 (72 - 88) | 96 (91 - 99) | 89 (83 - 95) | 91 (86 - 97) | 91 (85 - 96) |
Pulmonary Specialists | 92 (86 - 97) | 92 (86 - 97) | 84 (77 - 91) | 96 (92 - 99) | 92 (86 - 97) |
Round 1 Non-specialists | 81 (73 - 89) | 94 (89 - 99) | 86 (79 - 93) | 92 (86 - 97) | 90 (84 - 96) |
Round 2 Non-specialists | 86 (79 - 93) | 94 (89 - 98) | 86 (79 - 93) | 94 (89 - 99) | 91 (86 - 97) |
All Readers | 84 (77 - 92) | 94 (89 - 99) | 87 (80 - 94) | 93 (88 - 98) | 91 (85 - 97) |
Birt Hogg Dube Syndrome (N = 16) | |||||
Rad-specialists 1-2 | 78 (70 - 86) | 99 (97 - 99) | 94 (89 - 99) | 96 (92 - 99) | 95 (91 - 99) |
Rad-specialists 3-4 | 56 (46 - 66) | 98 (95 - 99) | 90 (84 - 96) | 92 (87 - 97) | 91 (86 - 97) |
Pulmonary Specialists | 56 (46 - 66) | 94 (90 - 99) | 68 (58 - 77) | 92 (86 - 97) | 88 (82 - 95) |
Round 1 Non-specialists | 81 (73 - 89) | 94 (89 - 99) | 73 (64 - 82) | 96 (92 - 99) | 92 (86 - 97) |
Round 2 Non-specialists | 77 (69 - 85) | 97 (94 - 99) | 86 (79 - 93) | 96 (91 - 99) | 94 (89 - 99) |
All Readers | 75 (66 - 84) | 96 (92 - 99) | 81 (73 - 89) | 95 (91 - 99) | 93 (87 - 98) |
Langerhans Cell Histiocytosis (N = 13) | |||||
Rad-specialists 1-2 | 88 (82 - 95) | 95 (91 - 99) | 76 (67 - 84) | 98 (96 - 99) | 94 (90 - 99) |
Rad-specialists 3-4 | 85 (77 - 92) | 92 (87 - 98) | 68 (59 - 77) | 98 (95 - 99) | 91 (86 - 97) |
Pulmonary Specialists | 58 (48 - 68) | 92 (87 - 98) | 54 (44 - 64) | 93 (88 - 98) | 88 (81 - 94) |
Round 1 Non-specialists | 75 (66 - 84) | 86 (79 - 93) | 47 (37 - 57) | 96 (92 - 99) | 85 (78 - 92) |
Round 2 Non-specialists | 68 (59 - 78) | 92 (87 - 97) | 59 (49 - 69) | 95 (91 - 99) | 89 (83 - 95) |
All Readers | 73 (64 - 82) | 90 (85 - 96) | 57 (47 - 67) | 96 (92 - 99) | 88 (82 - 94) |
Lymphocytic Interstitial Pneumonia (N = 7) | |||||
Rad-specialists 1 - 2 | 86 (79 - 93) | 95 (91 - 99) | 61 (51 - 70) | 99 (97 - 99) | 94 (90 - 99) |
Rad-specialists 3 - 4 | 57 (47 - 67) | 92 (87 - 98) | 51 (41 - 61) | 97 (93 - 99) | 90 (84 - 96) |
Pulmonary Specialists | 64 (55 - 74) | 96 (91 - 99) | 56 (46 - 66) | 97 (94 - 99) | 93 (88 - 98) |
Round 1 Non-specialists | 36 (26 - 45) | 97 (94 - 99) | 56 (46 - 65) | 95 (91 - 99) | 93 (88 - 98) |
Round 2 Non-specialists | 76 (68 - 85) | 93 (88 - 98) | 47 (37 - 57) | 98 (95 - 99) | 92 (86 - 97) |
All Readers | 60 (51 - 70) | 95 (90 - 99) | 52 (42 - 62) | 97 (93 - 99) | 92 (87 - 98) |
Cystic Lung Disease Mimics (N = 24) | |||||
Rad-specialists 1 - 2 | 96 (92 - 99) | 97 (93 - 99) | 91 (85 - 97) | 99 (96 - 99) | 96 (93 - 99) |
Rad-specialists 3 - 4 | 90 (84 - 96) | 94 (89 - 99) | 83 (76 - 92) | 96 (93 - 99) | 93 (88 - 98) |
Pulmonary Specialists | 84 (77 - 91) | 94 (90 - 99) | 85 (78 - 92) | 95 (90 - 99) | 92 (86 - 97) |
Round 1 Non-specialists | 80 (71 - 88) | 96 (92 - 99) | 88 (81 - 94) | 93 (88 - 98) | 92 (86 - 97) |
Round 2 Non-specialists | 77 (69 - 86) | 97 (94 - 99) | 92 (86 - 97) | 93 (87 - 98) | 92 (87 - 98) |
All Readers | 81 (74 - 89) | 96 (92 - 99) | 89 (83 - 95) | 94 (89 - 99) | 92 (87 - 98) |