Medicinal plant

Effect

Author

Year

Ref

Aloe vera

Acemannan

Induce Odontogenic differentiation

Root formation in Vital Pulp Therapy

Dentin bridge formation in pulp capping

Soudi A,

Vu TT

Songsiripradubboon S

Sholehvar F,

Jittapiromsak N,

2021

2020

2017

2016

2010

[43]

[57]

[58]

[59]

[60]

[61]

Astragalus membranaceus

Astragaloside IV

Differentiation effect in odontoblast-like MDPC-23 cells

Ding Q,

2019

[41]

Propolis

Odontogenic differentiation

Anti-inflammatory

Antibacterial

Dentinal de-sensibilization

Potentializes Bonding and sealing ability

Soudi A,

Mohanty S,

Shi B

Abdel Raheem IA,

Kim JH

El-Tayeb MM

Ahangari Z,

Abbasi AJ

Sabir A

Moradi S,

Ahangari

Sabir A

Al-shaher A

Bretz WA

Llewicz L

2021

2020

2019

2018

2017

2015

2012

2005

2004

1998

1986

1982

[43]

[62]

[63]

[64]

[65]

[66]

[67]

[68]

[69]

[70]

[71]

[72]

[73]

[74]

[75]

[76]

Curcuma longa

C. longa gel

Curcumin

Anti-inflammatory

Antibacterial

Antitumor

Enhancement of cells proliferation

Soudi A

Sinjari B

Prabhakar AR

2021

2019

[43]

[44]

[42]

Adipose tissue

Leptin

Enhancement in odontogenic differentiation

Angiogenetic

Reparative dentin formation as a pulp capping agent

Martin Gonzalez et al.

Choi SH

2022

2019

[77]

[78]

Allium sativum

GARLIC: Water extract/oil extract

Antibacterial

Healing potential

Mohammad SG,

2015

[46]

Caffeic acid

caffeic acid/mineral trioxide aggregate CAMTA˚

Angiogenic properties

Hydro-apatite formation

Odontogenic properties

Immunosuppressive properties

Tu MG,

Kuramoto

Grga et al

2020

2019

2008

[48]

[49]

[47]

Proanthocyanidins

Inhibiting demineralization of root dentin

Induce odontogenic differentiation

Increase the expression of biomineralization and odontogenic differentiation regulators: RUNX2, BMP2, OCN and DSPP

Zhou

Aydin B

Kulakowski D.

Chengfang

2020

2019

2017

2016

[51]

[52]

[40]

[50]

Hinokitiol Chamaecyparis taiwanensis

Antimicrobial

Enhancement in cell viability of dpscs and odontogenic differentiation

Lin CP

Shieh TM

Huang MH,

2019

2017

2016

[79]

[80]

[81]

Camellia sinensis

EGCG

Odontoblastic differentiation

Kwon YS,

2017

[45]

Cinnamomum verum

Cinnamaldehyde

In vitro/Evaluating odontogenic gene expression in hdpcs after treatment with cinnamaldehyde: Promotion in differentiation and proliferation of stem cells/No effect on ALP activity

Soudi A,

Kwon YS,

2021

2017

[43]

[45]

Schisandra chinensis

Anti-inflammatory, anti-oxidant and anti-cancer properties

Park

Kim

Park

2013

2010

2009

[55]

[56]

[53]