Periprocedural Complications: During the procedure or on the day of the procedure

Death

Severe vital complications other than death

(conversion to sternotomy, acute PCI, low cardiac output requiring mechanical circulatory support, cardiac tamponade, aortic dissection, or annular rupture)

1%

5%

(Survival rate 59.2%)

Postprocedural Complications

30-day mortality

1.1% - 3.0%

Cerebrovascular accident (CVA)

3% - 6%

Within 2 days

45%

3 - 10 days

28%

10 - 30 days

4%

1 month - 2 years

10.5%

Vascular Complications

Hematoma

Retroperitoneal bleeding

Arterial occlusion

Major bleeding 30 or more days after the procedure

High-degree AV block requiring permanent pacemaker implantation

Higher incidence than SAVR

Paravalvular regurgitation (PVR)

Hypotension

Transient ischemic attack (TIA)

Myocardial infarction (MI)

Acute kidney injury (AKI)

Long-Term Complications

Paravalvular regurgitation (PVR)

Endocarditis

Prosthetic valve thrombosis

Bleeding

5.9% with median onset at 132 days