Patient or population outcome: individuals at risk to develop pressure ulcers Settings: Acute healthcare setting, and Long healthcare setting Comparison: Other topical intervention, direct intervention or standard care |
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Authors & year | Outcome measure/ Follow up/ Assessment tool | Illustrative comparative risks | Relative effect CI 95% | Number of participants | Quality of evidence | Comments | |
Assumed risk | Corresponding risk | ||||||
Other /or standard intervention | Intervention | ||||||
[12] Non (inferiority study) | Incidence of pressure ulcer: olive oil vs Hyperoxygenated Fatty Acid. Follow up: up to 16 weeks. Assessment tool: Braden scale | HOFA: 394 Sacrum 8 (3.08) Rt heel 5 (1.92) Lt heel 3 (1.15) Rt trochanter 4 (1.54) Lt trochanter 1 (0.38) | Olive oil:437 Sacrum 8 (2.55) Rt heel 4 (1.27) Lt heel 3 (0.96) Rt trochanter 0 (0) Lt trochanter 1 (0.32) | R.R = 0.83 (0.42 - 1.64) | 831 | Low Due to risk of imprecision. | No difference in the findings between intervention of olive oil and control group of HOFA group. |
[8] | Incidence of pressure ulcer: silicon foam dressing vs fatty acids oil spry in addition to standard care. Follow up:14 days Assessment scale: Braden scale | Silicon foam dressing (n = 129) 3.9% (n = 5). Standard care (n = 202) 5% (n = 10) | Fatty acid oil (n = 130) 5.4% (n = 7) | Not estimated | 397 | Low Due to risk of imprecision. | Silicon foam dressing group showed lower incidence of pressure ulcer in comparison with Fatty acid oil group. |
[13] | Incidence of pressure ulcer: new topical agent (PARZINE-4A-SKR) vs placebo. Follow up: 14 days. Assessment scale: Braden scale | Average on Braden scale: 12.65+ - 1.82 (median = 12, extremes = 8 - 15). | Average on Braden scale: 12.28+ - 1.80 (median = 12, extremes = 5 - 9). | R.R = 0.82 (0.29 - 2.36) | 194 | Low Due to risk of imprecision. | No statistical significance of the intervention in comparison with the placebo. |
[10] | Incidence of pressure ulcer: Aloe-Vera gel vs standard care. Follow up: 10 days. Assessment tool: Braden scale. | 40 participants Frequency of PU = 8 (21.1%) | 40 participants Frequency of PU = 2 (5.1%) | Not estimated | 80 participants | Low Due to risk of bias and imprecision. | There was better outcomes in prevention pressure ulcer among intervention group (2/40 - 5.1%) in comparison with control group (8/40 - 21.1%). |
[11] | Development of pressure ulcer during the period of the study. Follow up: 6 months (after discharge). | Standard care: (n = 182) Incidence rate per 1000 patient days: 5.9 (2.8 - 12.4) | Five layered soft silicon foam (n = 182) Incidence rate per 1000 patient days: 0.7 (0.1 - 5.2) | Not estimated | 184 participants | Low Due to risk of bias and imprecision. | Silicon foam dressing had lower incidence of pressure ulcer in comparison with the standard dressing (0.7% vs 5.9%) |