Fibrinogen replacement

Volume per bag

Fibrinogen contents

Fibrinogen concentration

Increase of serum fibrinogen

Fresh frozen plasma

250 - 300 mL

250 - 500 mg

1 - 2 gr/L

15 - 30 mL/kg to increase 1 gr/L

Cryoprecipitate

10 - 20 mL

150 mg

12 - 15 gr/L

15 - 20 U to increase 1 gr/dL

Fibrinogen concentrate

50 mL

1000 mg

20 gr/L

50 mL increases 0.25 to 0.35 gr/L