ALP (U/L)

ALT (U/L)

AST (U/L)

TP (g/L)

Albumin (g/L)

Uric acid (mg/dL)

Effect of NA

Control 0 mg/kg

2991

5.0^x

353

36.3

13.4

3.8^xy

100 mg/kg

3128

4.4^y

342

36.1

13.3

3.6^y

300 mg/kg

3107

4.1^y

338

35.0

12.7

4.6^x

1000 mg/kg

2934

4.3^y

351

35.3

13.3

3.4^y

SEM

98.9

0.16

11.4

0.64

0.24

0.23

P-value (NA)

0.373

<0.001

0.755

0.327

0.088^†

0.004

P-value (Linear)

0.280

0.018

0.823

0.257

0.896

0.112

P-value (Quadratic)

0.241

<0.001

0.312

0.159

0.018

0.003

Effect of Sex

Female

2914^N

4.5

346

35.9

13.8^m

4.1^M

Male

3167^M

4.3

345

35.4

12.5ⁿ

3.6^N

SEM

87.7

0.14

8.1

0.58

0.25

0.17

P-value (Sex)

0.075

0.279

0.938

0.596

0.005

0.088

Effect of NA × Sex

Control 0 mg/kg

Female

2939

5.3

367

36.3

14.0

4.2

Male

3043

4.7

339

36.3

12.7

3.5

100 mg/kg

Female

2925

4.4

329

35.7

13.8

3.9

Male

3331

4.3

355

36.4

12.8

3.4

300 mg/kg

Female

2854

4.0

342

35.5

13.2

4.8

Male

3361

4.1

333

34.4

12.2

4.5

1000 mg/kg

Female

2936

4.4

348

36.0

14.3

3.5

Male

2932

4.1

354

34.6

12.2

3.2

SEM

139.9

0.22

16.2

0.91

0.34

0.33

P-value (Interaction)

0.165

0.354

0.414

0.549

0.173

0.854