3

1st FNA negative, from mediastinal LN: negative,

2nd biopsy from mediastinal LN negative,

3rd biopsy from peritoneal nodule: necrotizing granulomatosis positive for AFB

PCR: MT sensitive to anti-TB

Negative

Abdominal TB (LN, liver, peritoneum)

E.Coli septicemia

Possible fungal infection

IMPROVED

4

Sputum: smear and culture positive

PCR: MT sensitive to anti-TB

Positive

Lung and LN

None

IMPROVED

5

Sputum: smear and culture :positive

BM biopsy: necrotizing granuloma

PCR: MT sensitive to anti-TB

Positive

Lung, LN, liver, salivary glands, bone, and bone morrow

None

IMPROVED

6

BAL: smear negative, culture positive

PCR: MT sensitive to anti-TB

LN biopsy: necrotizing granuloma and AFB

BM biopsy: necrotizing granuloma

Positive

Lung, LN and bone marrow

None

IMPROVED

7

Sputum smear and culture: negative , Ileal Biopsy: necrotizing granuloma and presence of AFB

Positive

Lung, Ileum, liver, and LN

None

IMPROVED

8

Sputum: smear negative, culture negative

LN biopsy: necrotizing granuloma and AFB

Positive

Lung and LN

None

Improved from TB. Died after 2nd induction with systemic fungal infection (Trichosporon asheii)

9

BAL: MT

PCR: MT sensitive to anti-TB

Negative

Miliary TB

C.glabrata and C.Krusei in BAL

Died 2 weeks after diagnosis of leukemia with ARDS and septic shock

10

Sputum and BAL: negative

Positive

Lung and LN

None

IMPROVED on treatment.

11

Sputum: smear and culture positive

PCR: MT sensitive to anti-TB

Positive

Lung and LN

PSA septicemia

IMPROVED

12

Sputum/BAL: negative

Positive

Lung, pleural and LN (Miliary TB)

None

Died 3 weeks after diagnosis of leukemia with ARDS and septic shock