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Entry | Solvent | Tem. [˚C] | Time [min] | Yield [%]b |
1 | H2O | 25 | 14h | 40 c |
2 | H2O | 50 | 5 | 75 |
3 | H2O | 50 | 10 | 79 |
4 | H2O | 50 | 15 | 83 |
5 | H2O | 50 | 20 | 83 |
6 | H2O | 75 | 5 | 80 |
7 | H2O | 75 | 10 | 86 |
8 | H2O | 75 | 15 | 89 |
9 | H2O | 75 | 20 | 92 |
10 | H2O | 75 | 30 | 92 |
11 | H2O | 90 | 10 | 88 |
12 | H2O | 90 | 20 | 90 |
13 | H2O | 90 | 30 | 90 |
14 | EtOH | reflux | 20 | 91 |
15 | MeOH | reflux | 20 | 89 |
16 | Acetone | reflux | 20 | 70 |
17 | DMSO | 50 | 20 | 85 |
18 | THF | 50 | 20 | 77 |
19 | CHCl3 | reflux | 20 | 65 |
20 | No solvent | 75 | 20 | 79 |
21 | No solvent | 90 | 20 | 82 |
22 | No solvent | 90 | 30 | 87 |