Diagnosis

HC n = 38

BD n = 17

significant

differences

Sample name

young men n = 25

a

young women n = 10

b

old men n = 20

C

old women n = 20

d

young men n = 2

a

young women n = 10

b

old men n = 3

c

old women n = 2

d

Tryptophan

(μM)

63.92 ± 10.84

67.79 ± 9.30

68.89 ± 13.32

47.68 ± 7.19

57.71 ± 2.006

61.68 ± 16.96

78.50 ± 10.30

39.66 ± 11.91

*1

Serotonin

(nM)

1.29 ± 1.97

42.90 ± 35.49

68.61 ± 90.31

4.49 ± 6.03

302.0 ± 45.28

459.7 ± 402.5

250.3 ± 184.6

200.5 ± 128.0

*2

Kynurenine

(nM)

713.18 ± 136.02

1588.09 ± 313.52

1696.82 ± 1074.65

719.94 ± 173.87

1119.0 ± 161.08

1389.8 ± 342.36

2426.2 ± 628.86

914.89 ± 73.22

*3

5-Hydroxyindoleacetic acid

(nM)

9.00 ± 1.92

30.87 ± 9.55

33.15 ± 12.57

13.17 ± 3.30

10.62 ± 6.362

17.01 ± 13.09

29.83 ± 7.324

116.83 ± 27.63

*4