Variable | Number | Bivariate hazard Ratio (95% CI) | p | Multivariable hazard Ratio (95% CI) | p |
Female Male | 86 147 | 1.13 (0.79 - 1.63) | 0.47 |
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|
Age < 70 years Age ≥ 70 years | 147 86 | 0.34 (0.24 - 0.48) | <0.001 | 0.44 (0.30 - 0.65) | <0.001 |
No Previous CRC Previous CRC | 228 5 | 0.61 (0.19 - 1.93) | 0.40 |
|
|
No Resection at urgent operation Resection at urgent operation | 230 3 | 0.44 (0.11 - 1.77) | 0.25 |
|
|
No Venous invasion Venous invasion | 181 52 | 0.70 (0.48 - 1.04) | 0.08 |
|
|
No lymphatic vessel invasion Lymphatic vessel invasion | 156 77 | 0.49 (0.34 - 0.69) | <0.001 | 0.47 (0.32 - 0.68) | <0.001 |
No positive margin Positive margin | 212 21 | 0.16 (0.10 - 0.26) | <0.001 | 0.23 (0.14 - 0.39) | <0.001 |
Adenocarcinoma Mucinous adenoCa/ Signet ring | 208 25 | 0.68 (0.41 - 1.13) | 0.14 |
|
|
Neoadjuvant radiotherapy No neoadjuvant radiotherapy | 50 183 | 1.19 (0.78 - 1.80) | 0.41 |
|
|
Neoadjuvant chemotherapy No neoadjuvant chemotherapy | 32 201 | 1.07 (0.64 - 1.78) | 0.79 |
|
|
Adjuvant radiotherapy No adjuvant radiotherapy | 14 219 | 1.40 (0.73 - 2.67) | 0.31 |
|
|
Adjuvant chemotherapy No adjuvant chemotherapy | 147 86 | 0.34 (0.24 - 0.50) | < 0.001 | 0.50 (0.34 - 0.74) | 0.001 |
Number of nodes examined < 12 Number of nodes examined ≥ 12 | 60 173 | 1.30 (0.89 - 1.90) | 0.17 |
|
|
Number of comorbidities ≤ 1 Number of comorbidities > 1 | 179 54 | 0.55 (0.38 - 0.81) | 0.002 | 0.76 (0.51 - 1.12) | 0.16 |