| Dose < 1400 | Dose ≥ 1400 | Test value | p-value | Sig. | |||
No. | % | No. | % | |||||
Neurological toxicity | No | 13 | 34.2% | 6 | 17.6% | 7.463 | 0.024 | S |
G3,4 | 0 | 0.0% | 5 | 14.7% | ||||
G1,2 | 25 | 65.8% | 23 | 67.6% | ||||
Anemia | No | 28 | 73.7% | 19 | 55.9% | 3.905 | 0.142 | NS |
G3,4 | 0 | 0.0% | 2 | 5.9% | ||||
G1,2 | 10 | 26.3% | 13 | 38.2% | ||||
Thrombocytopenia | No | 37 | 97.4% | 26 | 76.5% | 7.165 | 0.007 | HS |
G3,4 | 0 | 0.0% | 0 | 0.0% | ||||
G1,2 | 1 | 2.6% | 8 | 23.5% | ||||
Neutropenia | No | 23 | 60.5% | 20 | 58.8% | 0.380 | 0.827 | NS |
G3,4 | 7 | 18.4% | 5 | 14.7% | ||||
G1,2 | 8 | 21.1% | 9 | 26.5% | ||||
Dermatological toxicity | No | 33 | 86.8% | 32 | 94.1% | 1.464 | 0.481 | NS |
G3,4 | 1 | 2.6% | 0 | 0.0% | ||||
G1,2 | 4 | 10.5% | 2 | 5.9% | ||||
Nausea | No | 26 | 68.4% | 24 | 70.6% | 1.290 | 0.525 | NS |
G3,4 | 0 | 0.0% | 1 | 2.9% | ||||
G1,2 | 12 | 31.6% | 9 | 26.5% | ||||
Vomiting | No | 25 | 65.8% | 27 | 79.4% | 1.660 | 0.198 | NS |
G3,4 | 0 | 0.0% | 0 | 0.0% | ||||
G1,2 | 13 | 34.2% | 7 | 20.6% | ||||
Diarhea | No | 17 | 44.7% | 17 | 50.0% | 1.613 | 0.446 | NS |
G3,4 | 4 | 10.5% | 1 | 2.9% | ||||
G1,2 | 17 | 44.7% | 16 | 47.1% | ||||
Allergy | No | 37 | 97.4% | 34 | 100.0% | 0.907 | 0.341 | NS |
G3,4 | 0 | 0.0% | 0 | 0.0% | ||||
G1,2 | 1 | 2.6% | 0 | 0.0% | ||||
Hepatic toxicity | No | 31 | 81.6% | 28 | 82.4% | 0.007 | 0.932 | NS |
G3,4 | 0 | 0.0% | 0 | 0.0% | ||||
G1,2 | 7 | 18.4% | 6 | 17.6% | ||||
Renal toxicity | No | 38 | 100.0% | 30 | 88.2% | 4.734 | 0.030 | S |
G3,4 | 0 | 0.0% | 0 | 0.0% | ||||
G1,2 | 0 | 0.0% | 4 | 11.8% | ||||
Oral mucositis | No | 28 | 73.7% | 27 | 79.4% | 0.876 | 0.645 | NS |
G3,4 | 3 | 7.9% | 1 | 2.9% | ||||
G1,2 | 7 | 18.4% | 6 | 17.6% | ||||
Fatigue | No | 32 | 84.2% | 25 | 73.5% | 1.308 | 0.520 | NS |
G3,4 | 1 | 2.6% | 2 | 5.9% | ||||
G1,2 | 5 | 13.2% | 7 | 20.6% | ||||
Others | Headache | 0 | 0.0% | 1 | 2.9% | 6.315 | 0.097 | NS |
Thrombophlebitis | 1 | 2.6% | 4 | 11.8% | ||||
Abdominal cramp | 1 | 2.6% | 5 | 14.7% | ||||
Phlebitis | 0 | 0.0% | 0 | 0.0% | ||||
Abdominal pain | 1 | 2.6% | 1 | 2.9% |