|
| <12 (n = 4) | <13 (n = 31) | P-value | >12 (n = 8) | > 13 (n = 43) | p-value | |||||
| No. | % | No. | % | No. | % | No. | % | ||||
| Age | <56 years | 2 | 50.0% | 11 | 35.5% | 0.762 | 4 | 50.0% | 24 | 55.8% | 0.572 |
| >56 years | 2 | 50.0% | 20 | 64.5% | 4 | 50.0% | 19 | 44.2% | |||
| Performance at presentation | 0 | 0 | 0.0% | 0 | 0.0% | 0.000 | 0 | 0.0% | 1 | 2.3% | 0.000 |
| 1 | 0 | 0.0% | 30 | 96.8% | 2 | 25.0% | 41 | 95.3% | |||
| 2 | 4 | 100.0% | 1 | 3.2% | 6 | 75.0% | 1 | 2.3% | |||
| Gender | Male | 0 | 0.0% | 31 | 100.0% | 0.000 | 1 | 12.5% | 43 | 100.0% | 0.000 |
| Female | 4 | 100.0% | 0 | 0.0% | 7 | 87.5% | 0 | 0.0% | |||
| Site of the tumor | Larynx | 0 | 0.0% | 31 | 100.0% | 0.000 | 3 | 37.5% | 43 | 100.0% | 0.000 |
| Hypopharynx | 4 | 100.0% | 0 | 0.0% | 5 | 62.5% | 0 | 0.0% | |||
| T-stage | 1, 2 | 0 | 0.0% | 12 | 38.7% | 0.124 | 3 | 37.5% | 22 | 51.2% | 0.477 |
| 3, 4 | 4 | 100.0% | 19 | 61.3% | 5 | 62.5% | 21 | 48.8% | |||
| N0 | 0 | 2 | 50.0% | 18 | 58.1% | 0.759 | 1 | 12.5% | 30 | 69.8% | 0.002 |
| 1, 2 | 2 | 50.0% | 13 | 41.9% | 7 | 87.5% | 13 | 30.2% | |||
| Metastases | M0 | 4 | 100.0% | 30 | 96.8% | 0.715 | 7 | 87.5% | 42 | 97.7% | 0.173 |
| M1 | 0 | 0.0% | 1 | 3.2% | 1 | 12.5% | 1 | 2.3% | |||
| Stage | 1, 2 | 0 | 0.0% | 7 | 22.6% | 0.092 | 1 | 12.5% | 19 | 44.2% | 0.288 |
| 3, 4 | 4 | 100.0% | 24 | 77.4% | 7 | 87.5% | 24 | 55.8% | |||
| Surgery | Yes | 0 | 0.0% | 15 | 48.4% | 0.362 | 2 | 25.0% | 19 | 44.2% | 0.092 |
| No | 4 | 100.0% | 13 | 41.9% | 6 | 75.0% | 21 | 48.8% | |||
| NA | 0 | 0.0% | 3 | 9.7% | 0 | 0.0% | 3 | 7.0% | |||
| Induction chemotherapy | Yes | 2 | 50.0% | 3 | 9.7% | 0.000 | 5 | 62.5% | 3 | 7.0% | 0.044 |
| No | 1 | 25.0% | 25 | 80.6% | 3 | 37.5% | 36 | 83.7% | |||
| NA | 1 | 25.0% | 3 | 9.7% | 0 | 0.0% | 4 | 9.3% | |||
| Radiation (alone or concurrent) | Yes | 3 | 75.0% | 21 | 67.7% | 0.132 | 4 | 50.0% | 31 | 72.1% | 0.436 |
| No | 0 | 0.0% | 7 | 22.6% | 4 | 50.0% | 8 | 18.6% | |||
| NA | 1 | 25.0% | 3 | 9.7% | 0 | 0.0% | 4 | 9.3% | |||
| RT dose | <66 | 3 | 100.0% | 20 | 83.3% | 0.159 | 1 | 25.0% | 21 | 61.8% | 0.444 |
| >66 | 0 | 0.0% | 4 | 16.7% | 3 | 75.0% | 13 | 38.2% | |||
| Concurrent chemoradiation CCRT | Yes | 2 | 50.0% | 10 | 32.3% | 0.402 | 2 | 25.0% | 17 | 39.5% | 0.413 |
| No | 1 | 25.0% | 18 | 58.1% | 6 | 75.0% | 22 | 51.2% | |||
| NA | 1 | 25.0% | 3 | 9.7% | 0 | 0.0% | 4 | 9.3% | |||
| Acute RT toxicity | No | 0 | 0.0% | 4 | 12.9% | 0.156 | 4 | 50.0% | 9 | 20.9% | 0.646 |
| NA | 1 | 25.0% | 3 | 9.7% | 0 | 0.0% | 3 | 7.0% | |||
| Mucositis | 3 | 75.0% | 21 | 67.7% | 2 | 25.0% | 26 | 60.5% | |||
| Skin reaction | 0 | 0.0% | 3 | 9.7% | 2 | 25.0% | 5 | 11.6% | |||