Hepatic neoplasm-related lesions

Control

(n = 10)

NDEA

(n = 10)

C3G-150

(n = 11)

MAEs-75

(n = 12)

MAEs-150

(n = 12)

Macroscopic lesions

Nodule incidence^#

0 (0)

10 (100)

8 (72.7)

7 (58.3)*

5(41.7)**

Max nodule diameter (mm)^▲

―

18.73 ± 7.13^a

9.42 ± 5.54^b

4.63 ± 2.46^c

1.87 ± 1.79^c

Average nodule number^#

ND

71.33 ± 62.11^a

48.10 ± 10.80^b

17.70 ± 3.42^d

6.13 ± 5.22^d

Microscopic lesions

AHF incidence

0 (0.0)

1 (10.0)

2 (16.7)

3 (25.0)

2 (16.7)

HA incidence

0 (0.0)

3 (30.0)

4 (33.3)

3 (25.0)

2 (16.7)

HCC incidence

0 (0.0)

5 (50.0)

3 (25.0)

2 (16.7)*

1 (8.3)**

Total tumor incidence

0 (0.0)

8 (80.0)

7 (58.3)

5 (41.7)

3 (25.0)*