| Groups | No. of animals | Ip administration | Gavage administration |
| Every Tuesday and Friday 8:30 am from 2 weeks to 12 weeks | Every day 10:00 am from 1 weeks to 18 weeks | ||
| Control | 10 | Physiological saline | Distilled water |
| NDEA | 12 | 25 mg/kg NDEA | Distilled water |
| C3G-150 | 12 | 25 mg/kg NDEA | 150 mg/kg C3G |
| low-dose MAE (MAEs-75) | 12 | 25 mg/kg NDEA | 75 mg/kg MAEs |
| high-dose MAEs (MAEs-150) | 12 | 25 mg/kg NDEA | 150 mg/kg MAEs |