All

n= 479 (100%)

2005

n= 176 (36.7%)

2023

N = 303 (63.3)

p

Male sex, n (%)

201 (42.0)

65 (36.9)

136 (44.9)

0.08

Median (interquartile range)

T2DM duration (years)

5.0 (1.0 - 11.0)

4.0 (2.0 - 9.0)

5.0 (0.0 - 12.0)

0.54

Age (years)

59.0 (53.0 - 68.0)

58.0 (52.0 - 66.0)

60.0 (53.0 - 68.0)

0.27

SBP (mmHg)

139.0 (125.0 - 157.0)

140.0 (124.0 - 159.5)

138.0 (125.0 - 156.0)

0.60

DBP (mmHg)

86.0 (78.0 - 96.0)

88.0 (79.0 - 97.0)

84.0 (77.0 - 94.0)

0.006

BMI (Kg/m²)

25.5 (22.2 - 30.2)

24.5 (21.3 - 28.3)

26.4 (22.7 - 31.1)

0.0003

WC (cm)

92.0 (82.0 - 101.0)

89.5 (79.0 - 96.0)

94.3 (83.0 - 103.0)

<0.0001

W/H

0.57 (0.51 - 0.63)

0.56 (0.50 - 0.61)

0.58 (0.52 - 0.64)

0.002

TC (mg/dl)

185.0 (151.4 - 211.7)

170.5 (142.0 - 201.5)

208.0 (162.1 - 224.0)

<0.0001

HDL-C (mg/dl)

52.0 (41.0 - 73.3)

41.0 (35.0 - 49.0)

61.7 (46.3 - 81.0)

<0.0001

LDL-C (mg/dl)

110.4 (90.0 - 146.7)

104.1 (81.9 - 128.5)

115.0 (96.3 - 152.0)

<0.0001

Non-HDL-C (mg/dl)

127.4 (100.3 - 158.2)

125.5 (103.0 - 154.5)

127.4 (100.3 - 162.1)

0.84

TG (mg/dl)

126.0 (88.4 - 163.5)

103.5 (73.5 - 140.5)

160.0 (154.0 - 166.0)

0.001

TG/HDL-C

2.3 (1.5 - 3.4)

2.6 (1.7 - 3.8)

2.1 (1.52 - 3.16)

0.01

Albumin (g/L)

-

-

3.53 (32.7 - 38.0)

-

Homa S (%)

75.9 (32.2 - 128.1)

113.0 (71.5 - 159.0)

45.3 (23.8 - 102.7)

<0.0001

Homa B (%)

38.1 (18.5 - 68.6)

28.0 (12.6 - 53.2)

46.6 (24.6 - 83.8)

<0.0001

Frequency, n (%)

T2DM without IR

204 (42.6)

100 (56.8)

104 (34.3)

<0.0001

T2DM with IR

177 (37.0)

23 (13.1)

154 (50.8)

<0.0001

MetS score ≥ 3/5

350 (73.1)

125 (71.0)

225 (74.3)

0.44

Overall obesity

126 (26.3)

30 (17.0)

96 (31.7)

0.0005

Abdominal obesity

208 (43.4)

57 (32.4)

151 (49.8)

0.0002

W/H > 0.5

196 (55.4)

57 (32.4)

139 (78.1)

<0.0001

TG/HDL-C ratio > 5.0

55 (11.6)

21 (11.9)

34 (11.4)

0.85