Brain region

Predictor variables

β

p

R2

Adjusted R2

Caudate nucleus

Intracranial volume

0.39

0.002

Years of cannabis use

−0.47

<0.001

Recent cannabis use

0.36

0.006

0.44

0.40

Pallidum

Intracranial volume

0.24

0.064

Years of cannabis use

−0.48

0.001

Recent cannabis use

0.35

0.012

0.33

0.29

Amygdala

Intracranial volume

0.28

0.033

Years of cannabis use

−0.46

0.001

Recent cannabis use

0.31

0.027

0.33

0.28

Putamen

Intracranial volume

0.30

0.028

Years of cannabis use

−0.38

0.011

Recent cannabis use

0.25

0.083

0.27

0.22

Nucleus accumbens

Intracranial volume

0.25

0.044

Years of cannabis use

−0.57

<0.0001

Recent cannabis use

0.23

0.084

0.39

0.35

Thalamus

Intracranial volume

0.47

<0.001

Years of cannabis use

−0.34

0.012

Recent cannabis use

0.22

0.086

0.39

0.35