Type of nanobiosensor

Samples

Advantages

Mechanical

Nanocantilever, acoustic biosensors

Highly mass sensitive, more the size decreases, more the mass reduces

Optical

Surface plasmon resonance (SPR), LSPR, FRET, SERS, evanescent field based devices, photonic crystal devices

Extremely sensitive, small volumes required, remarkable optical properties

Nanowire

Boron-doped silicon nanowires (SiNWs)

Analyte independent, sensitive, real time and quantitative fashion, biological and chemical species can be used.

Electronic

Lab on a chip

Each chip contains multiple sensors, hence different target DNA molecules can be addressed

PEBBLE

Poly (decyl methacrylate)-based fluorescent PEBBLE

Monitoring inter and intracellular ions and molecules in real time, high reversibility and stability to leaching and photo bleaching.

Nanoshell

Gold nanoshells

Rapid assays, enhance chemical sensing

Enzyme-based

4-Hydroxyphenylpyruvate Dioxygenase Enzyme

Precise and low cost techniques