Method

Advantage

Disadvantage

Clinical application

Example

Blood parameters

Basic assessment;

Easy to operate;

Cheap

Overall liver assessment;

Individual difference;

Only reflect liver damage

Most basic and widely used

Alb; bilirubin;

ALT; AST; PT

Comprehensive scoring systems

Basic assessment;

Non-individual difference;

Easy to operate;

Cheap

Overall liver assessment;

Not suitable for non-cirrhosis patients

Most basic and widely used

CTP-classification;

MELD score

Quantitative experiments

Accurate assessment;

Relatively easy to operation;

Relatively cheap

Overall liver assessment

only consider the effects of liver on drug intake and metabolism

Frequently used

ICG test

Liver volume measurement

Accurate assessment;

Local segment assessment;

Provide anatomical and functional information

Complex to operate;

Radioactivity expensive

Used only for academic research

99mTc-GSA

Gd-EOB-DTPA enhanced MRI

Accurate assessment;

Local segment assessment

Evaluation parameters and standards have not yet reached the unified standard;

Relatively expensive

Used only for academic research

Gd-EOB-DTPA enhanced MRI