| Day | Time Point | Parameter | Mean ± SD | Range (Min-Max) |
| Day-1 | Pre-dose (−2.00 to 0.00) | Systolic BP | 111.43 ± 3.368 | 106 - 118 |
|
|
| Diastolic BP | 70.57 ± 3.877 | 66 - 80 |
|
|
| Temperature | 97.57 ± 0.233 | 97.2 - 97.8 |
|
|
| Radial pulse | 71.00 ± 1.617 | 68 - 73 |
| Day-1 | 1.0 hrs | Systolic BP | 113.86 ± 4.185 | 108 - 124 |
|
|
| Diastolic BP | 71.57 ± 2.954 | 68 - 80 |
|
|
| Temperature | 97.31 ± 0.244 | 97 - 97.8 |
|
|
| Radial pulse | 71.86 ± 2.413 | 67 - 76 |
| Day-1 | 2.0 hrs | Systolic BP | 113.43 ± 2.980 | 110 - 120 |
|
|
| Diastolic BP | 71.71 ± 1.541 | 70 - 76 |
|
|
| Radial pulse | 71.21 ± 2.225 | 66 - 76 |
| Day-2 | Pre-dose (−2.00 to 0.00) | Systolic BP | 113.14 ± 4.130 | 106 - 120 |
|
|
| Diastolic BP | 72.29 ± 2.585 | 68 - 76 |
|
|
| Temperature | 97.47 ± 0.389 | 97 - 98.2 |
|
|
| Radial pulse | 70.93 ± 1.492 | 68 - 73 |
| Day-2 | 1.0 hrs | Systolic BP | 112.14 ± 2.983 | 108 - 118 |
|
|
| Diastolic BP | 71.43 ± 2.766 | 68 - 78 |
|
|
| Temperature | 97.77 ± 0.436 | 97 - 98.4 |
|
|
| Radial pulse | 70.29 ± 1.383 | 68 - 72 |
| Day-2 | 2.0 hrs | Systolic BP | 112.29 ± 3.750 | 108 - 120 |
|
|
| Diastolic BP | 71.71 ± 2.920 | 68 - 80 |
|
|
| Radial pulse | 72.00 ± 1.881 | 70 - 76 |
| Day-3 | Pre-dose (−2.00 to 0.00) | Systolic BP | 111.86 ± 1.834 | 110 - 116 |
|
|
| Diastolic BP | 74.07 ± 2.495 | 70 - 78 |
|
|
| Temperature | 97.39 ± 0.166 | 97.2 - 97.6 |
|
|
| Radial pulse | 74.21 ± 2.293 | 70 - 78 |
| Day-3 | 1.0 hrs | Systolic BP | 114.00 ± 3.328 | 110 - 118 |
|
|
| Diastolic BP | 74.00 ± 1.569 | 70 - 76 |
|
|
| Temperature | 97.37 ± 0.281 | 97 - 97.8 |
|
|
| Radial pulse | 72.57 ± 2.027 | 70 - 76 |
| Day-3 | 2.0 hrs | Systolic BP | 114.71 ± 2.164 | 112 - 118 |
|
|
| Diastolic BP | 73.86 ± 1.657 | 70 - 76 |
|
|
| Radial pulse | 72.36 ± 0.929 | 70 - 73 |
| Day-4 | At 9:00:00 AM | Systolic BP | 113.57 ± 2.102 | 110 - 116 |
|
|
| Diastolic BP | 73.86 ± 2.538 | 70 - 78 |
|
|
| Temperature | 97.40 ± 0.157 | 97.2 - 97.6 |
|
|
| Radial pulse | 75.21 ± 2.293 | 72 - 78 |
| Day-5 | At 9:00:00 AM | Systolic BP | 114.71 ± 3.474 | 110 - 120 |
|
|
| Diastolic BP | 73.43 ± 1.828 | 70 - 76 |
|
|
| Temperature | 97.50 ± 0.340 | 97 - 98 |
|
|
| Radial pulse | 73.29 ± 1.773 | 70 - 76 |
| Day-6 | Pre-dose (−2.00 to 0.00) | Systolic BP | 114.29 ± 4.890 | 106 - 122 |
|
|
| Diastolic BP | 72.57 ± 3.081 | 68 - 78 |
|
|
| Temperature | 97.61 ± 0.396 | 97 - 98.2 |
|
|
| Radial pulse | 71.29 ± 2.301 | 67 - 75 |
| Day-6 | 1.0 hrs | Systolic BP | 114.43 ± 4.380 | 106 - 122 |
|
|
| Diastolic BP | 73.29 ± 2.164 | 70 - 76 |
|
|
| Temperature | 97.66 ± 0.403 | 97 - 98.2 |
|
|
| Radial pulse | 71.50 ± 1.990 | 69 - 76 |
| Day-6 | 2.0 hrs | Systolic BP | 114.57 ± 4.033 | 110 - 122 |
|
|
| Diastolic BP | 73.00 ± 1.710 | 70 - 76 |
|
|
| Radial pulse | 72.21 ± 1.805 | 70 - 75 |
| Day-7 | Pre-dose (−2.00 to 0.00) | Systolic BP | 115.00 ± 4.946 | 106 - 124 |
|
|
| Diastolic BP | 73.14 ± 3.207 | 68 - 78 |
|
|
| Temperature | 97.73 ± 0.338 | 97 - 98.2 |
|
|
| Radial pulse | 72.29 ± 2.758 | 68 - 77 |
| Day-7 | 1.0 hrs | Systolic BP | 114.57 ± 3.458 | 110 - 122 |
|
|
| Diastolic BP | 72.43 ± 1.785 | 70 - 76 |
|
|
| Temperature | 97.50 ± 0.291 | 97.2 - 98 |
|
|
| Radial pulse | 71.86 ± 1.460 | 70 - 74 |
| Day-7 | 2.0 hrs | Systolic BP | 113.86 ± 3.718 | 110 - 120 |
|
|
| Diastolic BP | 72.43 ± 2.102 | 70 - 76 |
|
|
| Radial pulse | 71.50 ± 1.605 | 69 - 74 |
| Day-8 | Pre-dose (−2.00 to 0.00) | Systolic BP | 111.50 ± 3.391 | 105 - 118 |
|
|
| Diastolic BP | 71.21 ± 3.142 | 65 - 78 |
|
|
| Temperature | 97.81 ± 0.372 | 97 - 98.4 |
|
|
| Radial pulse | 71.79 ± 1.477 | 70 - 76 |
| Day-8 | 1.0 hrs | Systolic BP | 113.86 ± 2.878 | 108 - 118 |
|
|
| Diastolic BP | 72.00 ± 1.569 | 70 - 74 |
|
|
| Temperature | 97.66 ± 0.298 | 97.2 - 98.2 |
|
|
| Radial pulse | 72.43 ± 1.910 | 70 - 76 |
| Day-8 | 2.0 hrs | Systolic BP | 115.00 ± 2.572 | 110 - 120 |
|
|
| Diastolic BP | 71.71 ± 1.326 | 70 - 74 |
|
|
| Radial pulse | 72.21 ± 1.578 | 70 - 74 |