Item

Reference values

Group

Baseline

After 12 weeks

WBC (×10⁴/μL)

M:

3500

-

9700

Placebo

n = 50

5320

±

191

5056

±

195

F:

3500

-

9700

GK-1

n = 45

5309

±

156

5049

±

164

RBC (×10⁴/μL)

M:

438

-

577

Placebo

n = 50

457

±

6

460

±

7

F:

376

-

516

GK-1

n = 45

457

±

6

460

±

7

Hb (g/dL)

M:

13.6

-

18.3

Placebo

n = 50

14.1

±

0.2

13.9

±

0.2

F:

11.2

-

15.2

GK-1

n = 45

14.0

±

0.2

13.9

±

0.2

Ht (％)

M:

40.4

-

51.9

Placebo

n = 50

43.2

±

0.5

43.5

±

0.6

F:

34.3

-

45.2

GK-1

n = 45

43.2

±

0.5

43.5

±

0.6

PLT (×10⁴/μL)

M:

14.0

-

37.9

Placebo

n = 50

26.5

±

1.0

26.9

±

1.1

F:

14.0

-

37.9

GK-1

n = 45

27.3

±

0.8

27.4

±

0.9

TP (g/dL)

M:

6.5

-

8.2

Placebo

n = 50

7.06

±

0.05

7.10

±

0.06

F:

6.5

-

8.2

GK-1

n = 45

7.15

±

0.05

7.18

±

0.07

ALB (g/dL)

M:

3.7

-

5.5

Placebo

n = 50

4.39

±

0.03

4.38

±

0.04

F:

3.7

-

5.5

GK-1

n = 45

4.42

±

0.04

4.40

±

0.04

T-Bil (mg/dL)

M:

0.3

-

1.2

Placebo

n = 50

0.73

±

0.04

0.73

±

0.03

F:

0.3

-

1.2

GK-1

n = 45

0.74

±

0.04

0.74

±

0.04

D-Bil (mg/dL)

M:

0.0

-

0.4

Placebo

n = 50

0.236

±

0.014

0.228

±

0.013

F:

0.0

-

0.4

GK-1

n = 45

0.240

±

0.013

0.227

±

0.013

I-Bil (mg/dL)

M:

0.0

-

0.8

Placebo

n = 50

0.490

±

0.026

0.500

±

0.020

F:

0.0

-

0.8

GK-1

n = 45

0.502

±

0.027

0.516

±

0.025

ALP (U/L)

M:

38

-

113

Placebo

n = 50

61

±

2

63

±

2

F:

38

-

113

GK-1

n = 45

60

±

2

62

±

3

AST (U/L)

M:

10

-

40

Placebo

n = 50

21.0

±

0.7

20.7

±

0.9

F:

10

-

40

GK-1

n = 45

21.1

±

0.8

20.8

±

0.8

ALT (U/L)

M:

5

-

45

Placebo

n = 50

17

±

1

17

±

1

F:

5

-

45

GK-1

n = 45

18

±

1

19

±

1

LD (U/L)

M:

120

-

245

Placebo

n = 50

162

±

4

154

±

4

*

F:

120

-

245

GK-1

n = 45

169

±

5

162

±

5

*

γ-GTP (U/L)

M:

0

-

79

Placebo

n = 50

22.6

±

1.7

23.1

±

2.0

F:

0

-

48

GK-1

n = 45

21.1

±

1.9

21.9

±

2.0

T-Cho (mg/dL)

M:

150

-

219

Placebo

n = 50

201

±

4

205

±

4

F:

150

-

219

GK-1

n = 45

205

±

5

212

±

6

*

TG (mg/dL)

M:

50

-

149

Placebo

n = 50

73.0

±

5.4

75.1

±

5.9

F:

50

-

149

GK-1

n = 45

76.3

±

8.5

90.1

±

12.5

HDL-Cho (mg/dL)

M:

40

-

80

Placebo

n = 50

67.1

±

2.3

69.7

±

2.3

*

F:

40

-

90

GK-1

n = 45

67.9

±

2.5

69.9

±

2.8

LDL-Cho (mg/dL)

M:

70

-

139

Placebo

n = 50

116

±

4

115

±

4

F:

70

-

139

GK-1

n = 45

117

±

4

118

±

4

BUN (mg/dL)

M:

8.0

-

20.0

Placebo

n = 50

13.4

±

0.5

13.5

±

0.5

F:

8.0

-

20.0

GK-1

n = 45

12.6

±

0.5

12.9

±

0.5

CRE (mg/dL)

M:

0.65

-

1.09

Placebo

n = 50

0.702

±

0.021

0.735

±

0.020*

F:

0.46

-

0.82

GK-1

n = 45

0.675

±

0.022

0.692

±

0.022

UA (mg/dL)

M:

3.6

-

7.0

Placebo

n = 50

5.29

±

0.19

5.21

±

0.20

F:

2.7

-

7.0

GK-1

n = 45

5.05

±

0.20

5.07

±

0.21

Na (mEq/L)

M:

135

-

145

Placebo

n = 50

141

±

0

141

±

0

F:

135

-

145

GK-1

n = 45

141

±

0

141

±

0

K (mEq/L)

M:

3.5

-

5.0

Placebo

n = 50

4.42

±

0.04

4.39

±

0.04

F:

3.5

-

5.0

GK-1

n = 45

4.36

±

0.04

4.45

±

0.05

Cl (mEq/L)

M:

98

-

108

Placebo

n = 50

104

±

0

104

±

0

F:

98

-

108

GK-1

n = 45

104

±

0

104

±

0

GLU (mg/dL)

M:

70

-

109

Placebo

n = 50

89.2

±

1.0

89.3

±

1.1

F:

70

-

109

GK-1

n = 45

88.9

±

0.9

90.1

±

1.2