| Type of clinical adverse event (AE) | Patients | |
| Number of patients with AE | Frequency of patients with AE (%) | |
| General symptoms |
|
|
| Fatigue | 4 | 5.71 |
| Generalized pain | 2 | 2.86 |
| Chills | 2 | 2.86 |
| Thirst | 1 | 1.43 |
| Fever | 1 | 1.43 |
| Increased body temperature | 1 | 1.43 |
| Malaise | 1 | 1.43 |
| Ear, nose and throat |
|
|
| Rhinorrhea | 5 | 7.14 |
| Cough | 4 | 5.71 |
| Sneezing | 3 | 4.29 |
| Clearing of the throat | 1 | 1.43 |
| Eyes |
|
|
| Blurry vision | 1 | 1.43 |
| Neurologic |
|
|
| Headache | 11 | 15.71 |
| Psychiatric |
|
|
| Insomnia | 1 | 1.43 |
| Irritability | 1 | 1.43 |
| Skin |
|
|
| Rash | 8 | 11.43 |
| Generalized pruritus | 2 | 2.86 |
| Facial edema | 1 | 1.43 |
| Bones, joints and muscles |
|
|
| Arthralgia | 3 | 4.26 |
| Arthritis | 2 | 2.86 |
| Myalgia | 1 | 1.43 |
| Cardiopulmonary |
|
|
| Dyspnea | 1 | 1.43 |
| Tachycardia | 1 | 1.43 |
| Gastrointestinal |
|
|
| Nausea | 1 | 1.43 |
| Abdominal pain | 1 | 1.43 |
| Gynecology/Endocrine |
|
|
| Hot flashes | 1 | 1.43 |
| Polymenorrhea | 1 | 1.43 |
| Vaginal discharge | 1 | 1.43 |
| Other |
|
|
| Increased disease-related symptomatology | 7 | 10 |
| TOTAL | 70 | 100 |