Author and Year | Primary disease | Age at irradiation and Gender | Maximum radiation dose (Gy) | Estimated spinal cord dose at site of recurrence (Gy) | Latency period (years) | Tumor type | Tumor location in spine | Follow-up period |
Clifton et al., 1980 | Hodgkin’s disease | 21 M | 50 | 49.69 | 6 | GBM | Cervico-thoracic | 10 wks* |
Steinbock, 1980 | Pulmonary tuberculosis | 20 - 23 F | Unable to calculate | Unable to calculate | 25 | Low-grade astrocytoma | Cervico-thoracic | 27 months |
Marus et al., 1986 | Thyroid cancer | 19 F | 58 | 45 - 55 | 23 | Anaplastic astrocytoma | Upper thoracic | 20 months* |
Bazan et al., 1990 | Hodgkin’s disease | 19 M | 40 | Not calculated | 7 | Grade II - III astrocytoma | Cervical | 6 months |
Grabb et al., 1996 | Medullomyo blastoma | 3 F | 54.4 | 30.0 | 17 | Anaplastic astrocytoma | Cervical | 4 months* |
Riffaud et al., 2006 | Hodgkin’s disease | 30 M | 40 | Not calculated | 9 | Malignant glioma | Cervico-thoracic | Unknown |
Yeung et al., 2006 | Nasopharyngeal carcinoma | 28 F | 86 | Not calculated | 7 | GBM | Cervical | 8 months |
Ng et al., 2007 | Hodgkin’s disease | 23 M | 30.60 | Not calculated | 3 | GBM | Thoracic | Unknown, weeks* |
Ahn & Kim 2012 | Nasopharyngeal Rhabdomyosarcoma | 4 F | 45 | Not calculated
| 13 | GBM | cervical | 8 months |
Kawanabe et al. 2012 | Testicular seminoma | 18M | 30.6 | Not Calculated | 37 | Anaplastic astrocytoma | thoracic | 9 M* |
Present case | Squamous cell carcinoma of the tongue base | 50 M | 73 | 40 - 50 | 7 | GBM | Cervical | 7 months* |