n = 5

baseline

4 weeks

8 weeks

12 weeks

P value

Total score

14.8 ± 6.2

10.2 ± 8.2

4.8 ± 2.5

9 ± 7.4

0.11

Subscale score

Delusions

1.2 ± 2.7

0.6 ± 0.9

0 ± 0

0.2 ± 0.4

0.51

Hallucinations

0.2 ± 0.4

1.0 ± 1.2

0.2 ± 0.4

0.4 ± 0.9

0.3

Agitation/Agression

1.4 ± 1.9

0.6 ± 0.9

0.2 ± 0.4

0 ± 0

0.39

Dysphoria/Depression

1.0 ± 1.2

1.2 ± 2.7

0.6 ± 0.5

0.2 ± 0.4

0.48

Anxiety

3.0 ± 3.3

3.4 ± 4.2

0.6 ± 0.5

3.0 ± 5.1

0.24

Euphoria

0 ± 0

0.8 ± 1.8

0 ± 0

0 ± 0

0.39

Apathy

6.2 ± 4.7

2.0 ± 3.4

1.0 ± 1.7

3.8 ± 4.0

0.038*

Disinhibition

1.0 ± 1.7

0 ± 0

0 ± 0

0.2 ± 0.4

0.3

Irritability

0.8 ± 1.3

0.6 ± 0.9

1.4 ± 2.6

0 ± 0

0.32

Abberant Motor Behavior

0 ± 0

0 ± 0

0.8 ± 1.1

1.2 ± 1.6

0.11

Sleep and Night-Time Behavior Change

2.8 ± 3.9

1.6 ± 3.6

1.6 ± 3.6

0.8 ± 1.8

0.26

Appetite and Eating change

2.6 ± 1.9

1.6 ± 2.2

1.0 ± 1.7

1.6 ± 3.6

0.33