Group

AM baseline

(Day −2)

Day 28

Day 56

Day 84

AM

Decrease

% Decrease

AM

Decrease

% Decrease

AM

Decrease

% Decrease

1

357.1

182.9

174.3

48.8

314.4

42.7

12.0

315.7

41.4

11.6

2

399.8

11.0

388.8

97.2

0.3

399.5

99.9

0.4

399.4

99.9

3

404.4

5.5

398.9

98.6

0.1

404.3

>99.9

0.0

404.4

100