| Day | Procedure |
| −7 to −1 | Acclimation period |
| −7 to 27* | Antimicrobial treatment |
| −7 to 84 | Observed dogs daily for clinical normality Monitored environmental parameters in cage environment |
| −7 | Clinical examinations Body weights Biopsies (food to be removed the afternoon prior to Day −7) |
| −2 | Clinical examinations Photographic documentation Mite counts and clinical assessments Body weights |
| −1 | Randomization |
| 0 | Appropriate treatment dose administration to Groups 2 and 3 (according to Day −2 weight) Specific post-administration health observation (hourly up to four hours after IVP administration) |
| 14 | Clinical examinations |
| 27 | Body weights Biopsies |
| 28 | Clinical examinations Photographic documentation Mite counts and clinical assessments Appropriate treatment dose administration to Groups 2 and 3 (according to Day 27 weight) Specific post-administration health observation (hourly up to four hours after IVP administration) |
| 42 | Clinical examinations |
| 55 | Body weights |
| 56 | Clinical examinations Photographic documentation Mite counts and clinical assessments Appropriate treatment dose administration to Groups 2 and 3 (according to Day 55 weight) Specific post-administration health observation (hourly up to four hours after IVP administration) |
| 70 | Clinical examinations |
| 84 | Body weights Clinical examinations Photographic documentation Mite counts and clinical assessments |