| Percent of shared ancestry | UPEC | Iguana | Fresh water | Seawater | Top similarity |
| UPEC | GTG5 | 52 | 36 | 48 | Iguana |
| UPEC | BOX | 44 | 28 | 56 | Seawater |
| Iguana | 41 | GTG5 | 31 | 28 | UPEC |
| Iguana | 28 | BOX | 49 | 15 | Fresh water |
| Fresh water | 63 | 55 | GTG5 | 72 | Seawater |
| Fresh water | 72 | 36 | BOX | 27 | UPEC |
| Marine water | 80 | 30 | 40 | GTG5 | UPEC |
| Marine water | 80 | 70 | 30 | BOX | UPEC |