|
| Evidence-based treatment protocols | Guide recommendation |
| First line drugs | Lithium salt + valproic acid | Naltrexone added to conventional treatment |
| Treatment of emotional symptoms | ||
| Lithium salts (teenagers) | If taking lithium salts, add valproic acid | |
| Taking naltrexone to reduce alcohol consumption | ||
| Second line drugs | None | Lamotrigine monotherapy or add-on therapy |
| Valproic acid monotherapy or add-on therapy | ||
| Addition of disulfiram | ||
| If naltrexone is not effective in helping patients to quit drinking, switch to acamprosate | ||
| Three lines drugs | None | Add gabapentin |
| Addition of topiramate | ||
|
|
| Lithium salt |
| If acamprosate and naltrexone do not work to stop drinking, consider disulfiram | ||
| Drugs with insufficient evidence | Acetic acid | None |
| Aripiprazole | ||
| Gabapentin | ||
| Icariside | ||
| Lamotrigine | ||
| Naltrexone | ||
| Topiramate | ||
| Disulfiram | ||
| No medication recommended | Quetiapine monotherapy or add-on therapy | Quetiapine monotherapy or add-on therapy |