Drug combinations

Control drugs

Manic relapse

Depression relapse

Intermittent symptoms

Valproic acid + lithium

Valproic acid

+

+/−

−

Valproic acid + lithium

Lithium

+/−

−

−

Valproic acid + lithium

Carbamazepine

−

−

−

Lamotrigine + Valproic acid

Lamotrigine

+/−

+

−

Lamotrigine + Lithium

Lithium

−

+/−

−

Lamotrigine + Lithium

Olanzapine + Lithium

−

−

+/−

Quetiapine + Lamotrigine

Quetiapine

+/−

−

−

Asenapine + lithium/valproic acid

Lithium/valeric acid

−

−

−