Gene variants | Subpopulations | Genotypes | Cases | Controls | p-value | OR (95% CI) | Bonf | *p-value |
SET8 rs16917496 | Premenopausal | CC | 68 (93.15) | 158 (81.44) | - | - | - | 0.0166 |
| CT | 5 (6.85) | 34 (17.53) | 0.03 | 2.93 (1.1 - 7.8) | 0,042 | ||
| TT | 0 (0.00) | 2 (1.03) | 0.62 | 2.16 (0.22 - 221.14) | 1 | ||
| CT + TT | 5 (6.85) | 36 (18.56) | 0.018 | 3.1 (1.21 - 7.93) | 0.036 | ||
Postmenopausal | CC | 24 (75) | 24 (82.76) | - | - | - | 0.4599 | |
| CT | 8 (25) | 5 (17.24) | 0.46 | 0.63 (0.19 - 2.1) | 1 | ||
| TT | 0 (0.0) | 0 (0.0) | 1 | 1 (0.06 - 16.9) | 1 | ||
Bantu | CC | 28 (84.85) | 33 (80.49) | - | - | - | 0.4937 | |
| CT | 5 (15.15) | 7 (17.07) | 0.79 | 1.19 (0.35 - 3.98) | 1 | ||
| TT | 0 (0.0) | 1 (2.44) | 0.56 | 2.6 (0.22 - 29.61) | 1 | ||
| CT + TT | 5 (15.15) | 8 (19.51) | 0.62 | 1.3 (0.42 - 4.43) |
| ||
Semi-bantu | CC | 64 (88.89) | 149 (81.87) | - | - | - | 0.1546 | |
| CT | 8 (11.11) | 32 (17.58) | 0.20 | 1.72 (0.77 - 3.86) | 0.4 | ||
| TT | 0 (0.0) | 1 (0.55) | 0.88 | 1.3 (0.12 - 14.53) | 1 | ||
| CT + TT | 8 (11.11) | 33 (18.13) | 0.17 | 1.78 (0.79 - 3.98) | 0.2 | ||
TP53 rs1042522 | Premenopausal | CC | 36 (49.32) | 138 (71.13) | - | - | - | 0.00085 |
| CG | 37 (50.68) | 56 (28.87) | 0.001 | 0.39 (0.23 - 0.69) | 0.002 |