Preformed secretory granule mediators · Histamine · Proteoglycans · Serine proteases · Chymases · Tryptases · Carboxypeptidase A |
Lipid-derived mediators (newly formed) · Leukotriene · Leukotriene C4, D4, and E4 (SRS-A) · Prostaglandin D2 · Platelet-activating factor (PAF) |
Mast cell-derived cytokines Proinflammatory Cytokines · TNF-a · IL-1a · IL-1b · IL-6 · MIP family |
Mitogenic cytokines and/or growth factors · IL-3 · IL-4 · IL-5 · IL-10 · GM-CSF |
Immunodulatory cytokines · IL-1a and IL-1b · IL-4 · IL-10 · IFN-y |