Experimental model | Solved disease | Experimental material | The experimental results | Reference |
3D human-tissue models | Atherosclerosis | Paclitaxel (PTX) | It suggested excellent biological characteristics and potential treatment effects of the nanoparticles optimized in vitro | [1] |
3D model set up by crosslinking HA with alginate | Breast cancer | Hyaluronan (HA) | The invasion and migration abilities of 4T-1 and SKBR3 cells are significantly enhanced by the presence of HA35 | [2] |
nanostructured 3D grids fabricated using electro-spinning technique | Screening of new drugs | Electrospun scaffolds | The scaffolds are transparent and thus allow observation of viable cells in time; standard fluorescence or colorimetric methods such can be used for evaluation of cells | [6] |
Inflamed mucosa model (colon) | Chronic IBD (colon) | Budesonide/ fluoreceinamine | Prolonged anti-inflammatory effect was observed for 4 days | [18] |
3D skin model | Skin | Squalene | Superior defensive and anti-wrinkle actions of squalane loaded fullerene-C60 was reported | [19] |