Patient Characteristics

All Surgeries

Open Transcranial

Trans-sphenoidal

P value

Total Patients

341

299 (87.6%)

42 (12.3%)

Adult/Children

272/69

237/62

35/7

0.088

Mean Age (range) (years)

34.88 (1 - 74)

31.47 (1 - 74)

31.48 (6 - 66)

Sex (male/female)

202/139

181/118

21/21

0.102

CP prehistory

23

21

2

0.778

Presenting Symptoms

Endocrine disturbance

213 (62.5%)

184

29

0.105

Visual impairment

219 (64.2%)

188

31

0.084

Headache

192 (56.3%)

168

24

0.830

Nausea and Vomiting

52 (15.2%)

43

9

0.723

Diabetes Inspidus

53 (15.5%)

42

9

0.505

Dizziness

45 (13.2%)

40

5

0.454

Amenorrhea

23

19

4

0.125

Growth Retardation

17

13

4

0.150

Weakness of Limbs

16

14

2

0.424

Hydrocephalus

15

15

0

0.497

Memory Decline

10

9

1

0.230

Weight Gain/Loss

7

7

0

0.318

Sexual Behavior Disturbance

6

6

0

0.836

Fever

6

6

0

0.932

Psycho-Behavioral changes

5

4

1

0.595

Gait Instability

5

5

0

0.834

Tinnitus

3

3

0

0.871

Seizure

2

1

1

0.489

Accidental finding following TBI imaging

2

2

0

0.902

Tumor features

Cystic

129 (37.8%)

109

20

0.970

Solid

88 (23.8%)

75

13

0.952

Mixed

124 (36.4%)

115

9

0.926

Calcification

139 (40.8%)

125

14

0.504

Suprasellar

198 (58.1%)

189

9

<0.0001*

Intrasellar

40 (11.7%)

10

30

<0.0001*

Intra-third ventricular

103 (30.2%)

100

3

0.638

Surgical Treatment and Outcome

Extent of Resection (GTR/STR)

247/94

220/89

27/15

0.208

Postoperative outcome (good/poor)

324/17

284/14

39/3

0.822