Molecules

Interval between taking and dosing (hour)

Target serum concentrations (mg/l)

Concentration requiring therapeutic adjustment (mg/l)

Ethambutol

2 - 3

2 - 6

<2

Rifampicin

2

8 - 24

<6

Isoniazid

1-2

3 - 6

<2

Pyrazinamid

1-2

20 - 40

<15