1) Age at disease onset < 40 years

Development of symptoms or findings related to Takayasu arteritis at age < 40 years

2) Claudication of extremities

Development and worsening of fatigue and discomfort in muscles of 1 or more extremity while in use, especially the upper extremities

3) Decreased brachial artery pulse

Decreased pulsation of 1 or both brachial arteries

4) BP difference > 10 mm Hg

Difference of >10 mm Hg in systolic blood pressure between arms

5) Bruit over subclavian arteries or aorta

Bruit audible on auscultation over 1 or both subclavian arteries or abdominal aorta

6) Arteriogram abnormality

Arteriographic narrowing or occlusion of the entire aorta, its primary branches, or large arteries in the proximal upper or lower extremities, not due to arteriosclerosis, fibromuscular dysplasia, or similar causes; changes usually focal or segmental