Authors | Site of fracture | Study design | Results |
Jansen J et al. (2011) [75] | Vertebral fractures | Meta-analysis of 8 RCTs | All BPs reduced the risk of fractures with zoledronate providing the greatest reduction of all BPs |
Shi L et al. (2019) [76] | Vertebral fractures | Meta-analysis involving 11,822 patients with osteoporotic fractures | BPs significantly reduced the risk of new vertebral, and nonvertebral fractures with alendronate being the best intervention for secondary prevention than the other BPs |
Climet v et al. [77] | Distal radial fractures | RCT | No statistically significant differences in fracture healing rate in alendronate and placebo groups with significantly improved bone mass in the alendronate group |
Rosental et al. (2009) [78] and Shoji KE (2018) [79] | Distal radial fractures | RCT | No significant differences in fracture healing time, clinical or functional outcomes in conservatively treated DRF patients in BP users and BP naive patients. |