Product name


Product specifications and properties



Life Cell Corp, Brachburg, US

Introduced 2008, licensed in Europe and US, porcine-derived, non-crosslinked, undergoes a minimally manipulative manufacturing process with the aim to eliminate the alpha-Gal epitope, thickness 1 - 2 mm provides chemotaxis and suppresses apoptotic induction [37] loses tensile strength significantly in a mouse model between 30 days and 3 months [38] [39]

Seems to elicit an intense early immune response in mouse models [40] [41] with later shift to beneficial M2:M1 ratio around day 35 [41]

Observed collagen deposition at later time points in mouse models [38] [39] [40]

Breast Reconstruction

Abdominal Wall Repair

Epiflex ®

DIZG mbH, Berlin, Germany

Human-skin derived, non crosslinked, thickness >0.3 and >0.8 mm [42]

preservation of significant ECM components such as collagen type I, type III, type IV, fibronectin, laminin, vitronectin and hyaluronic acid seem to be preserved after decellularization, small amounts of donor DNA remain

Breast Reconstruction

Hypertrophic Scar Treatment

Dermis Replacement

Soft Tissue Replacement


DECO med s.r.l., Venice, Italy

pre-shaped, non-crosslinked, 0.6 mm thick, porcine-derived matrix, shows mild fibroblastic reaction and ingrowth of blood vessels after 1 yr in humans [43] , no chemical preservatives used during manufacturing process

Breast Reconstruction