Markers | HCC (n = 40) | Non-HCC (n = 20) | Sensitivity | Specificity | Positive Predictive Value | Negative Predictive Value | Accuracy | ||
True Positive | False Negative | True Negative | False Positive | ||||||
GPC3 (≥3.15 ng/ml) | 33 | 7 | 19 | 1 | 82% (67 - 0.93) | 95% (75 - 0.99) | 97% (83 - 0.99) | 73% (58 -0 .84) | 87% (75 - 0.94) |
AFP (≥257 ng/ml) | 31 | 9 | 17 | 3 | 77% (61 - 0.89) | 85% (62 - 0.97) | 91% (78 - 0.97) | 65% (51 - 0.77) | 80% (68 - 0.89) |
Both GPC3 & AFP | 29 | 11 | 20 | 0 | 72% (56 - 0.85) | 100% (83 - 0.100) | 100% | 64% (52 - .75) | 82% (69 - 0.90) |