Overall survival rate

Disease-free survival rates

The baseline characteristics before RFA

P value

The baseline characteristics before RFA

P value

Age, younger (<70): older (≥70)

NS (0.748)

Age, younger (<70): older (≥70)

NS (0.233)

Gender, male: female

NS (0.843)

Gender, male: female

NS (0.650)

Child-Pugh, Class A: Class B

0.007

Child-Pugh, Class A: Class B

NS (0.163)

Serum AFP level, <100 ng/mL: ≥100 ng/mL

NS (0.551)

Serum AFP level, <100 ng/mL: ≥100 ng/mL

NS (0.390)

Serum PIVKA-2 level, <100 ng/mL: ≥100 ng/mL

NS (0.092)

Serum PIVKA-2 level, <100 ng/mL: ≥100 ng/mL

NS (0.088)

The clinic-pathologic characteristics related to RFA

The clinic-pathologic characteristics related to RFA

Tumor size, <20 mm: ≥20 mm

NS (0.962)

Tumor size, <20 mm: ≥20 mm

NS (0.640)

Ablated margin, <5 mm: ≥5 mm

NS (0.087)

Ablated margin, <5 mm: ≥5 mm

NS (0.616)

RFA alone: combined RFA and TACE

NS (0.097)

RFA alone: Combined RFA and TACE

NS (0.950)

Local recurrence

NS (0.92)

Local recurrence

NS (0.071)

The characteristics before hepatectomy

The characteristics before hepatectomy

Child-Pugh, Class A: Class B

NS (0.286)

Child-Pugh, Class A: Class B

0.004

Serum AFP level, <100 ng/mL: ≥100 ng/mL

NS (0.704)

Serum AFP level, <100 ng/mL: ≥100 ng/mL

NS (0.348)

Serum PIVKA-2 level, <100 ng/mL: ≥100 ng/mL

NS (0.775)

Serum PIVKA-2 level, <100 ng/mL: ≥100 ng/mL

NS (0.235)

Resected tumor size, <5 cm: ≥5 cm

NS (0.950)

Resected tumor size, <5 cm: ≥5 cm

NS (0.879)

The characteristics after hepatectomy

The characteristics after hepatectomy

Microvascular invasion, positive: negative

NS (0.097)

Microvascular invasion, positive: negative

NS (0.521)

Differentiation, poorly: moderate/well

NS (0.852)

Differentiation, poorly: moderate/well

NS (0.743)

Recurrence interval, <1 year: ≥1 year

NS (0.468)

Recurrence interval, <1 year: ≥1 year

NS (0.227)