Steroid pulse -therapy in patients. With coronavirus Pneumonia (COVID-19), systemic inflammation And Risk of venous thrombosis and thromboembolism (WAYFARER Study)11

Russia

17 patients with severe coronavirus pneumonia using retrospective comparison analysis (control group, n = 17).

34 patients with a proven diagnosis of coronavirus pneumonia who were admitted to the Medical Research and Educational Center of Lomonosov Moscow State University.

agents, it was decided to perform pulse treatment with high doses GCs: MP 1000 mg intravenously for 3 days with subsequent dexamethasone 4 mg twice a day for 3 - 7 days.

therapy with MP 1000 mg for 3 days and dexamethasone 8 mg for another 3 - 5 days

High-dose pulse GC therapy has a rapid anti-inflammatory effect; however, it increases the NLR and the D-dimer levels, which increase the risk of venous thromboembolism