Dose and duration of Cd administered | Tissue/Animal | Response to Cd exposure | Reference |
0.1, 0.5, 1.0 and 2.0 mg/L for 30 days | Male Swiss albino mice | Dose-dependent increase of ROS in blood stream Reduced CAT, SOD and GSH-Px enzyme activity in liver, kidney, spleen, testis and brain | [10] |
15 mg/kg b.w./day single dose 15 mg/kg b.w./day for 60 days | Male Wistar albino rats | Significant increase in CAT and MDA levels in erythrocytes compared to control group Significant increase in CAT, GSH-Px, SOD and MDA in erythrocytes compared to control group | [11] |
30 mg/kg b.w. for 21 days | Male Wistar rats | Significant increase in MDA levels in blood stream Significant reduction in GSH, SOD and CAT levels in blood stream | [37] |
15 and 100 ppm for 60 days | Male Wistar rats | Increased CAT and SOD levels in heart tissue at 15 ppm dose Significant increase in CAT levels in heart tissue at 100 ppm | [38] |
40 mg/L for 6 weeks | Male albino rats | Significant decreases of CAT, SOD and reduced GSH in plasma significantly reducing the total antioxidant capacity Significant increase in MDA levels in plasma | [39] |
5 mg/kg b.w. for 30 days | Adult male albino Wistar mice | Liver CAT, SOD, GRx and GST were significantly reduced while liver MDA was significantly increased | [40] |
50 mg/L for 12 weeks | Male Wistar rats | Decreased activity of SOD and GPx while reducing levels of GSH and total antioxidant capacity in liver tissues | [41] |
10 and 50 ppm for 30 days | Female Sprague-Dawley rats | Elevated blood plasma MT levels till 7 days after exposure and reduced blood plasma MT levels in the following 2 weeks. | [42] |