Variable

Overall survival

Univariate

Multivariate

HR

(95% CI)

p

HR

(95% CI)

padjusted

Skeletal mass index (cm2/m2)

0.97

(0.94 to 0.99)

0.01

0.99

(0.95 to 1.02)

0.57

Age (Years)

1.01

(0.99 to 1.02)

0.36

1.01

(0.99 to 1.03)

0.20

BMI (Kg/m2)

0.95

(0.91 to 0.98)

0.01

0.97

(0.93 to 1.01)

0.29

Pretreatment Neutrophil count (mm3)

1.07

(1.01 to 1.13)

0.01

1.02

(0.94 to 1.12)

0.51

Pretreatment Platelet count (mm3)

1.00

(1.00 to 1.00)

0.7

0.99

(0.99 to 1.00)

0.89

High pretreatment Haemoglobin (g/dL)

0.78

(0.69 to 0.86)

<0.001

0.79

(0.69 to 0.91)

<0.001

Normal pretreatment creatinine (mg/dL)

1.2

(0.59 to 2.41)

0.61

0.59

(0.25 to 1.39)

0.23

Histological type

0.57

(0.27 to 1.18)

0.13

1.20

(0.27 to 1.38)

0.24

Incomplete CCTR

2.07

(1.28 to 3.31)

<0.001

2.69

(1.55 to 4.67)

<0.001

Advanced Stage

1.71

(0.99 to 2.92)

0.05

1.20

(0.63 to 2.28)

0.57