Variable

Progression free survival

Univariate

Multivariate

HR

(95% CI)

p

HR

(95% CI)

padjusted

Skeletal mass index (cm2/m2)

0.97

(0.94 to 0.99)

0.01

0.99

(0.96 to 1.03)

0.93

Age (Years)

1.00

(0.98 to 1.02)

0.68

1.00

(0.98 to 1.02)

0.88

BMI (Kg/m2)

0.96

(0.92 to 0.99)

<0.001

0.98

(0.94 to 1.02)

0.58

Pretreatment Neutrophil count (mm3)

1.09

(1.03 to 1.14)

<0.001

1.01

(0.93 to 1.10)

0.64

Pretreatment Platelet count (mm3)

1.00

(1.00 to 1.00)

0.7

1.00

(0.99 to 1.00)

0.40

Pretreatment Haemoglobin (g/dL)

0.73

(0.66 to 0.81)

<0.001

0.73

(0.64 to 0.84)

<0.001

Pretreatment creatinine (mg/dL)

1.80

(0.95 to 3.43)

0.07

0.85

(0.40 to 1.83)

0.69

Histological type

0.73

(0.36 to 1.46)

0.37

1.12

(0.53 to 2.35)

0.75

Incomplete CCTR

1.95

(1.23 to 3.11)

<0.001

2.84

(1.64 to 4.91)

˂0.001

Advanced Stage

1.99

(1.16 to 3.43)

0.01

1.09

(0.57 to 2.07)

0.79